Continuity: After entering room 304, Leonard steps on the bed to put the 4 photos back up on his paper on the wall. In the 1st close-up he puts the Discount Inn and the 2nd close-up he puts up Natalie. Then in a wide shot of Leonard looking at the paper, visible at the top of the paper, in the center, is the photo of Natalie and on it's right is the photo of Teddy, already up. In the next shot, the 3rd close-up, he puts up his car. However in the next wide shot ALL three photos that he just put up in the close-ups are GONE. Then in the 4th close-up he puts up Teddy's photo, which was up in the first wide shot.

Continuity: In the scene in which Leonard writes on the back of his picture of Teddy, "He is the one. Kill him," we see a shot of Leonard placing the picture on top of his tan jacket on the bed as he goes to write on it. Then, it goes to a close-up of the picture in which the jacket has disappeared and the picture is lying directly on the blue bedspread. It actually happens twice within that same scene.

Continuity: There are scenes in which Leonard is looking at the back of Teddy's polaroid. If you look at the serial number of the polaroid when he is writing "Don't believe his lies" it is a different number than when he looks at it during the beginning of the film.

Visible crew/equipment: When Dodd pulls in behind Leonard in the alley the crew is reflected in his SUV.

Visible crew/equipment: Teddy, Leonard and Jimmy leave Jimmy's motel room and Leonard tells Teddy, "Take your own car." In the next shot as Teddy reaches for his door, a crew member, plus another one under his arm/elbow, are very clearly visible in the door mirror. Then as Teddy closes the door a crew member's face is seen on the left, in that mirror.

Continuity: At the beginning of the movie, Leonard looks outside his window and sees room 304 (which will be given later to him on top of his current room) - it is on the same floor he is currently on. Still, when he learns from the clerk that he has been ripped off, we see them both coming out of room 21, which probably is room 221 with the first 2 missing, because it's next to the reception, itself located on the second floor (we know that because from room 304, Leonard only needs to go down one flight of stairs to reach it). Both his rooms, 304 and 221, could not possibly have been on the same floor.

Factual error: In the beginning, Leonard looks at a copy of John G/Teddy's driver's license. The expiration date is listed as 2-29-01, but of course, 2001 was not a leap year, so there would've only been 28 days in the month.

Continuity: When Leonard snaps a picture of Jimmy's body his head is lying between his shoulders looking straight up, but in the polaroid his head is lying to the right, and it is, in fact, a different actor altogether.

Continuity: When Natalie writes the 'Dodd' note at her home, it just reads, "Dodd, MonteRest Inn on 5th St., room 6, put him onto Teddy..." However when Leonard reads the note in the car and at the motel, the note now reads, "Dodd, white guy, 6'2", blonde, MonteRest Inn on 5th St..."

Continuity: At Natalie's house, when she is leaving and Lenny is taking a picture of her, the background looks totally different than from what is shown on the picture: the curtains are opened wider, the door is half open, there is a lamp on the left and there is no mirror on the wall.

Revealing: In the Sammy/Lenny shot in the Institution, before the switch the orderly on the left heads toward the medical files with his arm outstretched and the nurse walks behind Sammy. Just as the person passes the camera the film jerks and the two men at the table, visible on the left, have a shaking motion. After the switch, the orderly and the nurse are both further back.

Continuity: When Dodd is in the closet, gagged with duct tape, the piece of tape reaches his cheekbones. Yet when Leonard rips the strip of duct tape to put across Dodd's mouth, it is considerably longer, long enough to reach his ears.

Continuity: The blood pattern splattered on the tile wall and grout, shown in the photograph that Teddy holds in the opening shot, differs from the pattern that is seen in the reverse shot while Teddy is still lying on the ground, before he even moves.

Visible crew/equipment: As Leonard stands in the bathroom looking at Dodd, unconscious on the floor after the two fought, visible in the reflection of the mirror behind him is a dark haired crew member with a blue shirt. It's in the same shot as the housekeeping woman that knocks.

Continuity: Leonard shows up at Natalie's door and shows her the picture of Dodd. However when Leonard actually takes that photo of Dodd, not only does his face differ, the blood on his face differs from the photograph as well.

Continuity: Leonard is twice shown looking at the back of the Ferdy's Bar coaster, with 'Come by after, Natalie' written on the back. The handwriting is noticeably different in the two shots, particularly the first two letters of 'after' and the middle 'a' in 'Natalie'.

Continuity: When Leonard is looking at the note that reads, "Dodd white guy...get rid of him for Natalie..." in the wide shots as Leonard holds just the note, many photos are lying on the bed under his hands. Yet in the next close-up, the suit is spread out right under his hands as he holds the note with a single photo, that he soon drops, and no other photos are seen.

Continuity: In the first close-up Teddy's eyeglasses are upside down, lying near the tile wall, the next wide shot it's upright, further away from the wall, next close-up it's near the tile wall again, lying on the grout just as it's moving in reverse, then in the next wide shot it's further away from the wall once again, lying on the tile, just before it reverses to go back up onto his face.

Continuity: In Natalie's bedroom, as Leonard is dressing, she sits at her vanity table, picks up a bright red hair pick and pulls her hair up with it. Just before kissing him, in the shot facing Leonard, the pick in her hair is lavender.

Continuity: While Leonard sits on Natalie's couch rifling through his papers, in the shot facing Leonard, behind him, the two top drawers of the writing desk are open. In the next shot as Natalie comes home only the top drawer is open.